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QuickView for Endothelin 1;jsessionid=4D2597E63F0C3267AA4843428E560249;jsessionid=7874E4E1B8E9A5DDDA01703E068837BC (gene)


Gene Symbol:
EDN1 Bos taurus Bos taurus
Full name:
endothelin 1
Synonyms:
N/A
Genomic Location:
Chr 23: 44797047-44804030
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Gallus gallus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_181010
Protein Names
P17322
Q3T0C1



GO Molecular Function

endothelin A receptor binding | signaling receptor binding | bombesin receptor binding | hormone activity | neuropeptide receptor binding | molecular function regulator | endothelin B receptor binding | protein binding | receptor regulator activity | G-protein coupled receptor binding | receptor ligand activity | cytokine activity

GO Biological Process

regulation of JUN kinase activity | positive regulation of smooth muscle cell proliferation | positive regulation of heart contraction | positive regulation of striated muscle cell differentiation | regulation of supramolecular fiber organization | respiratory gaseous exchange | positive regulation of sarcomere organization | regulation of blood vessel diameter | regulation of muscle system process | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | positive regulation of blood circulation | regulation of systemic arterial blood pressure by hormone | positive regulation of cellular component organization | intracellular signal transduction | regulation of cell development | regulation of localization | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | positive regulation of striated muscle tissue development | phospholipase D-activating G-protein coupled receptor signaling pathway | vascular smooth muscle contraction | hormone secretion | regulation of cardiac muscle cell differentiation | establishment of localization | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | negative regulation of RNA biosynthetic process | regulation of heart growth | negative regulation of nitric-oxide synthase biosynthetic process | cell differentiation | response to drug | cellular chemical homeostasis | inositol phosphate-mediated signaling | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | tonic smooth muscle contraction | regulation of renal sodium excretion | mesenchyme development | blood vessel morphogenesis | pattern specification process | artery smooth muscle contraction | positive regulation of cellular biosynthetic process | cellular process | unsaturated fatty acid biosynthetic process | secretion | peptide hormone secretion | regulation of cell motility | localization | cellular homeostasis | epithelial tube morphogenesis | regulation of cell growth involved in cardiac muscle cell development | regulation of mitotic nuclear division | negative regulation of nucleic acid-templated transcription | regulation of striated muscle tissue development | positive regulation of protein kinase activity | response to hypoxia | positive regulation of oxidoreductase activity | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | positive regulation of cardiac muscle hypertrophy | positive regulation of muscle cell differentiation | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | epithelium development | positive regulation of renal sodium excretion | icosanoid biosynthetic process | smooth muscle contraction | regulation of urine volume | cellular component organization | cellular lipid metabolic process | regulation of systemic arterial blood pressure mediated by a chemical signal | calcium ion homeostasis | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | positive regulation of stress-activated protein kinase signaling cascade | muscle contraction | branching involved in blood vessel morphogenesis | response to stimulus | vasculature development | regulation of sarcomere organization | mesenchymal cell development | monocarboxylic acid metabolic process | regulation of excretion | positive regulation of protein metabolic process | regulation of blood vessel size | response to stress | regulation of cell proliferation | tube morphogenesis | regulation of blood circulation | phosphatidylinositol-mediated signaling | regulation of heart rate | secretion by cell | cardiovascular system development | positive regulation of hormone secretion | hormone activity | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | regulation of cellular component size | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | cartilage development | modulation of chemical synaptic transmission | cellular biosynthetic process | dorsal/ventral pattern formation | embryo development | cell-cell signaling | molecular function regulator | metal ion homeostasis | blood vessel development | negative regulation of blood vessel diameter | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | system development | response to oxygen levels | regulation of signal transduction | positive regulation of urine volume | positive regulation of organelle organization | regulation of actin cytoskeleton organization | multicellular organism development | regulation of MAPK cascade | positive regulation of organelle assembly | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | positive regulation of muscle organ development | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of actomyosin structure organization | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | rhythmic synaptic transmission | positive regulation of secretion | organic substance transport | regulation of blood pressure | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | protein kinase C deactivation | animal organ morphogenesis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of JNK cascade | small molecule metabolic process | peptide transport | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | second-messenger-mediated signaling | stem cell differentiation | positive regulation of cell migration | fatty acid biosynthetic process | biosynthetic process | regulation of cellular protein metabolic process | vasoconstriction | angiogenesis | middle ear morphogenesis | lipid biosynthetic process | inositol lipid-mediated signaling | regulation of systemic arterial blood pressure by endothelin | positive regulation of cell growth involved in cardiac muscle cell development | regulation of heart contraction | cation homeostasis | sensory organ development | chordate embryonic development | peptide secretion | cellular cation homeostasis | endocrine process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of signal transduction | rhythmic excitation | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | protein kinase C-activating G-protein coupled receptor signaling pathway | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | regulation of tube size | positive regulation of transport | embryonic morphogenesis | regulation of mitotic cell cycle | carboxylic acid metabolic process | positive regulation of molecular function | calcium-mediated signaling | embryonic organ morphogenesis | positive regulation of heart rate | regulation of signaling receptor activity | receptor regulator activity | positive regulation of organ growth | regulation of cardiac muscle hypertrophy | regionalization | positive regulation of protein modification process | regulation of growth | vein smooth muscle contraction | regulation of cardiac muscle tissue development | tissue morphogenesis | branching morphogenesis of an epithelial tube | regulation of pH | regulation of kinase activity | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | phosphatidylinositol 3-kinase signaling | anatomical structure development | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | cell surface receptor signaling pathway | regulation of vasoconstriction | metabolic process | positive regulation of cell development | regulation of receptor biosynthetic process | mesenchymal cell differentiation | positive regulation of supramolecular fiber organization | regulation of RNA biosynthetic process | regulation of body fluid levels | negative regulation of transcription, DNA-templated | embryonic organ development | regulation of tube diameter | ear development | amide transport | chemical homeostasis | prostaglandin metabolic process | regulation of secretion | body fluid secretion | receptor ligand activity | hormone transport | positive regulation of cellular component biogenesis | cytokine activity | organic substance metabolic process | connective tissue development | negative regulation of biosynthetic process | negative regulation of gene expression | nitric oxide transport | regulation of glucose transmembrane transport | animal organ development | negative regulation of cellular protein metabolic process | positive regulation of kinase activity | ion homeostasis | positive regulation of prostaglandin-endoperoxide synthase activity | regulation of striated muscle cell differentiation | regulation of phosphate metabolic process | phospholipase C-activating G-protein coupled receptor signaling pathway | renal system process | fatty acid metabolic process | positive regulation of muscle tissue development | regulation of JNK cascade | positive regulation of MAPK cascade | drug transport | stem cell development | morphogenesis of a branching epithelium | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | positive regulation of cardiac muscle cell differentiation | icosanoid metabolic process | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of stress-activated MAPK cascade | regulation of cell communication | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | cell development | regulation of developmental growth | organic acid metabolic process | positive regulation of phosphorylation | regulation of cell size | morphogenesis of a branching structure | anatomical structure morphogenesis | positive regulation of MAP kinase activity | regulation of organ growth | regulation of developmental process | regulation of G-protein coupled receptor protein signaling pathway | developmental process | regulation of muscle cell differentiation | positive regulation of cell cycle process | regulation of cell growth | positive regulation of cell size | negative regulation of transcription by RNA polymerase II | tube development | regulation of transport | positive regulation of transcription, DNA-templated | neurotransmitter transport | positive regulation of nucleic acid-templated transcription | signal release | positive regulation of heart growth | prostaglandin biosynthetic process | neural crest cell differentiation | cellular metal ion homeostasis | positive regulation of transcription by RNA polymerase II | positive regulation of JUN kinase activity | in utero embryonic development | positive regulation of metabolic process | regulation of actin filament-based process | skeletal system development | cellular metabolic process | positive regulation of receptor biosynthetic process | positive regulation of cardiac muscle tissue development | regulation of smooth muscle cell proliferation | positive regulation of cell motility | regulation of organelle assembly | circulatory system development | ear morphogenesis | divalent inorganic cation homeostasis | neural crest cell development | regulation of cellular component organization | regulation of cytoskeleton organization | muscle system process | positive regulation of signaling | positive regulation of mitotic nuclear division | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of muscle organ development | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

cell | cytoplasm | extracellular region | extracellular space | intracellular